UNEXPLAINED HIGH-ACTIVITY OF ASPARTATE-AMINOTRANSFERASE (EC-2.6.1.1) - A CASE-REPORT

Authors
DEJONGE N HOUWING A
Citation
N. Dejonge et A. Houwing, UNEXPLAINED HIGH-ACTIVITY OF ASPARTATE-AMINOTRANSFERASE (EC-2.6.1.1) - A CASE-REPORT, Netherlands journal of medicine, 48(6), 1996, pp. 224-226
Citations number
23
Categorie Soggetti
Medicine, General & Internal
Journal title
Netherlands journal of medicine → ACNP
ISSN journal
03002977
Volume
48
Issue
6
Year of publication
1996
Pages
224 - 226
Database
ISI
SICI code
0300-2977(1996)48:6<224:UHOA(->2.0.ZU;2-B
Abstract
We report a case of unexplained and persistently elevated ASAT activit y in serum, This appeared to be due to a macro-enzyme of ASAT, as was demonstrated by protein-A-Sepharose(R) treatment of the serum sample. Although macro-ASAT seems to be clinically irrelevant, unexplained rai sed ASAT activity without acknowledgement of its macroenzyme nature ma y lead to unnecessary diagnostic procedures.