ANTIBIOTIC-INDUCED PROLONGED CHOLESTASIS - POSSIBLY DUE TO CEFTIBUTEN

Authors
COMBE C BANAS B ZOLLER W MANNS MP SCHLONDORFF D
Citation
C. Combe et al., ANTIBIOTIC-INDUCED PROLONGED CHOLESTASIS - POSSIBLY DUE TO CEFTIBUTEN, Zeitschrift fur Gastroenterologie, 34(7), 1996, pp. 434-437
Citations number
19
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
Zeitschrift fur Gastroenterologie → ACNP
ISSN journal
00442771
Volume
34
Issue
7
Year of publication
1996
Pages
434 - 437
Database
ISI
SICI code
0044-2771(1996)34:7<434:APC-PD>2.0.ZU;2-N
Abstract
We report on a 43-year-old female diabetic patient who was treated wit h ceftibuten because of Pseudomonas aeruginosa induced otitis externa. Thereafter she developed a prolonged seven-months-persisting irrevers ible cholestasis. Liver puncutre revealed a canalicular and hepatocell ular cholestasis without liver cell necrosis or bile duct injury. Afte r seven-months the patient died because of antibiotic-resistant Pseudo monas-septicemia.