The Onsager regression hypothesis states that the regression of fluctu
ations is governed by macroscopic equations describing the approach to
equilibrium. It is here asserted that this hypothesis fails in the qu
antum case. This is shown first by explicit calculation for the exampl
e of quantum Brownian motion of an oscillator and then in general from
the fluctuation-dissipation theorem. It is asserted that the correct
generalization of the Onsager hypothesis is the fluctuation-dissipatio
n theorem.