ANIMAL-MODELS OF DEMYELINATION

In the past year, animal studies on central nervous system demyelinati on have focused on therapeutic strategies and the functional character ization of T-cells, cytokines, and adhesion molecules. Significant pro gress has been realized in the treatment of animals with experimentall y induced demyelinating disease using glial cell transplants, autoanti bodies, cytokines, growth factors, and by inhibiting adhesion molecule s and cytokines, In this review, we summarize the important contributi ons made in those respective areas.