There are many differences in the clinical features of intussusception
between African and temperate countries. The records of 192 patients
with intussusception who presented to the Pediatric Surgical Service a
t King Edward VIII Hospital, Durban, South Africa during a 10-year per
iod were reviewed. Compared with temperate countries, the patients wer
e older (median, 1 year 7 months), presented later (median, 4.2 days),
had a higher proportion of colo-colic lesions (17%), had absence of p
rimary bowel pathology, and had a high surgical rate (82%). To define
clinically important differences, the clinical and pathological featur
es of 158 cases of ileo-colic intussusceptions were compared with 34 c
olo-colic cases. Compared with the ileo-colic group, colo-colic lesion
s occurred in older children (median, 3.8 years) (v 1.5 years; P < .00
1). In the colo-colic group, there were fewer shocked and pyrexial pat
ients, and the rate of successful nonoperative reduction was higher. T
he groups had a similar incidence of surgical intervention (82%). In t
he ileo-colic group, there was a higher mortality rate and more compli
cations, but only the higher resection rate (P < .001) was statistical
ly significant. Copyright (C) 1996 by W.B. Saunders Company.