ENZYMATIC-HYDROLYSIS OF MESO(SYN-SYN)-1,3,5-TRIACETOXY-2,4-DIMETHYLPENTANE AND ACETYLATION OF (SYN-SYN)-3-BENZYLOXY-2,4-DIMETHYLPENTANE-1,5-DIOL BY LIPASE
S. Nagumo et al., ENZYMATIC-HYDROLYSIS OF MESO(SYN-SYN)-1,3,5-TRIACETOXY-2,4-DIMETHYLPENTANE AND ACETYLATION OF (SYN-SYN)-3-BENZYLOXY-2,4-DIMETHYLPENTANE-1,5-DIOL BY LIPASE, Chemical and Pharmaceutical Bulletin, 44(7), 1996, pp. 1391-1394
Chiral inductions of meso triacetate (4) and meso diol (15) were carri
ed out on the basis of enzymatic reaction using lipase to give chiral
synthons having three consecutive chiral centers with high enantiomeri
c excess.