An infant with repaired esophageal atresia presented with several appa
rent life-threatening events (ALTEs). He had upper airway instability,
gastroesophageal reflux (GER), and tracheomalacia. Oxygen breathing t
est results showed a modest increase in arterial PO2 consistent with t
he development of an intrapulmonary shunt from absorption collapse of
some hypoventilated areas of the lung. Glossopexy was followed by impr
ovement in upper airway stability, normal oxygen test, and disappearan
ce of ALTE. These findings support the concept that upper airway insta
bility, obstructive apnea, lower airway instability, absorpion collaps
e, massive intrapulmonary shunt, and ALTE are the result of a cascade
reaction. The authors conclude that infants with ALTE associated with
obstructive apnea and O-2 shunting require glossopexy to reduce the ri
sk of sudden death. Copyright (C) 1996 by W.B. Saunders Company