The incidence of a significant hemorrhage in the natural history of ca
vernomas is below 1% per year, but the risk of a second hemorrhage in
patients with initial bleeding cavernomas is between 14% and 29%, in t
he light of these figures, all cavernomas ought to be resected if surg
ical-related morbidity can be minimized. Stereotactically guided neuro
surgery offers the advantage of planning the least traumatic approach
before craniotomy due to the knowledge of the exact localisation of th
e lesion. During a 2-year period 12 patients (age 16-54 years) with in
tracranial supratentorial cavernomas (size 0.5-1.8 cm) were treated by
stereotactically guided microsurgery. The cavernomas were seated in a
depth between 0.4 and 4.5 cm. 4 patients had an overt hemorrhage in t
heir history. in six cases a seizure was the first symptom (altogether
8 patients had seizures preoperatively). Two patients were asymptomat
ic. Standard CRW (Cosman, Roberts, Wells) stereotactic system was used
in all cases. The skin incision and the osteoplastic craniotomy(mean
diameter 2.8 cm) were planned stereotactically. In 11 patients a trans
sulcal approach was used. The size of the corticotomy could be limited
to less than 1 cm. Using the stereotactic method, all cavernomas were
found with a high degree of accuracy. After lesionectomy a total of 1
to 2 mm of the surrounding yellow-stained brain tissue was sucked awa
y because it contains hemosiderin and therefore iron, which may have a
n epileptogenic effect. No relevant surgical-related neurological morb
idity was found in any patient a half year after surgery. Seven out of
eight patients were free of seizures. One still had problems.