Because of the limits of justice, our society turns itself towards the
medical need and demands efficient treatments. Mutilating neuro-surge
ry and treatment with estrogens have been used and then stopped. Medro
xyprogestrone (MPA) and Cyproterone (CPA) acetate have been proved to
be efficient in 80% of cases studied and published. However the therap
eutic use of CPA is limited in France by three drawbacks : exclusive o
ral route of administration, lack of available biological criteria as
a control of good observance and lack of official indication. Therefor
e the authors studied a GnRH analogue (triptoreline) which induces a r
eversible hormonal castration and which is administered by I.M. route
monthly, It was efficient in five out of six aggressive hypersexual pa
tients. An ethical study is proposed afterwhich the authors call for a
n evolution of the mentalities about this question.