Modern surgery of the macula exists since 1965, and was initially prop
osed in membrane removal from patients presenting an idiopathic epiret
inal membrane. This first indication authorized the development of mac
ular microsurgical instrumentation and further analysis of membrane fr
agments. However, the exact pathogenesis of these membranes remains ye
t unknown. Since 1991 macular surgery was applied in the treatment of
macular holes. Results obtained after macular hole surgery confirmed p
athogenic hypothesis observed clinically by Gass. Considerable improve
ment was therefore acheived in anatomical and functional outcome. Chor
ioretinal adhesion agents were recently proposed to optimize the closu
re of macular holes. Submacular surgery is the latest technologic ache
ivement under investigation. The ultimate indications are age-related
macular degeneration, first cause of blindness in industrialized count
ries. Retinal transplantation opens new avenues in the treatment of a
large number of chorioretinal diseases, The assessement of macular sur
gery could pave the way in realising such technical advances.