OBJECTIVE AND IMPORTANCE: Cavernous sinus thrombophlebitis is a rare,
dangerous, and historically difficult condition to diagnose and treat.
Knowledge of the imaging findings and the importance of early diagnos
is and treatment are emphasized. CLINICAL PRESENTATION: We present a c
ase of cavernous sinus thrombophlebitis caused by sphenoid sinusitis.
Previously undescribed magnetic resonance imaging findings of cavernou
s sinus thrombophlebitis include enlargement of the cavernous sinus, a
bnormal enhancement and increased T2 signal of the petrous apex and cl
ivus, and marked narrowing of the cavernous portion of the internal ca
rotid artery. Resolution of cavernous sinus thrombophlebitis is also d
ocumented by magnetic resonance imaging. INTERVENTION: The anatomy of
the cavernous sinus dictates the natural history and diagnosis of cave
rnous sinus thrombophlebitis. We review the literature regarding the c
linical diagnosis, differential diagnosis, and treatment of cavernous
sinus thrombophlebitis. CONCLUSION: We emphasize the importance of a h
igh index of suspicion, the potentially rapid and fatal course of the
disease process, and the subsequent need for antibiotic therapy and se
lective surgery.