HISTIOCYTOSIS-X OF THE THYROID-GLAND

Histiocytosis X rarely involves the thyroid gland and occurs as one of the unusual manifestations of systemic diseases, Diagnosis is based o n the identification of the Langerhans' cells in an appropriate backgr ound, We report a case of histiocytosis X confined to the thyroid glan d that represents the primary manifestation of the disease, A careful histological, immunohistochemical and ultrastructural study has been p erformed and problems of differential diagnosis are discussed.