T. Fujishita et al., A CASE OF SMALL-CELL CARCINOMA OF THE LUNG ASSOCIATED WITH HYPERTROPHIC PULMONARY OSTEOARTHROPATHY, Tumori, 82(3), 1996, pp. 259-261
A 73-year-old man had complained of painful swelling in the upper and
lower extremities for several months before detection of small cell lu
ng carcinoma, A bone scan showed abnormal symmetrical accumulations in
the extremities, but periosteal proliferation was not demonstrated by
X-ray, When a complete remission was obtained by chemoradiotherapy, t
he joint manifestation also subsided completely. In almost all reporte
d cases, hypertrophic pulmonary osteoarthropathy was observed in patie
nts with non-small cell lung carcinoma. To our knowledge, this is the
first case report of hypertrophic pulmonary osteoarthropathy associate
d with small cell lung carcinoma published in the English literature.