LINEAR AMIDES AS SUBSTANCE-P ANTAGONISTS

Authors
TEALL M HARRISON T MOSELEY JD OWENS AP SADOWSKI S CASCIERI MA
Citation
M. Teall et al., LINEAR AMIDES AS SUBSTANCE-P ANTAGONISTS, Bioorganic & medicinal chemistry letters, 6(13), 1996, pp. 1585-1588
Citations number
5
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
6
Issue
13
Year of publication
1996
Pages
1585 - 1588
Database
ISI
SICI code
0960-894X(1996)6:13<1585:LAASA>2.0.ZU;2-4
Abstract
In the present study we demonstrate that an amide linking group provid es an excellent template for the positioning of a benzhydryl group and a suitably functionalized aromatic ring in an orientation which allow s for high affinity binding to the hNK(1) receptor. Copyright (C) 1996 Elsevier Science Ltd