THE VALUE OF THE ULTRASTRUCTURAL PATTERN OF MYELOPEROXIDASE AND PLATELETPEROXIDASE IN IDENTIFICATION OF 2 BLASTIC CELL-TYPES DURING TRANSFORMATION OF A CHRONIC MYELOPROLIFERATIVE DISORDER

Authors
MOLDOVEANU E MOICEAN A COLITA A HALALAU F
Citation
E. Moldoveanu et al., THE VALUE OF THE ULTRASTRUCTURAL PATTERN OF MYELOPEROXIDASE AND PLATELETPEROXIDASE IN IDENTIFICATION OF 2 BLASTIC CELL-TYPES DURING TRANSFORMATION OF A CHRONIC MYELOPROLIFERATIVE DISORDER, Haematologia, 27(3), 1996, pp. 135-141
Citations number
16
Categorie Soggetti
Hematology
Journal title
Haematologia → ACNP
ISSN journal
00176559
Volume
27
Issue
3
Year of publication
1996
Pages
135 - 141
Database
ISI
SICI code
0017-6559(1996)27:3<135:TVOTUP>2.0.ZU;2-G
Abstract
The value of the ultrastructural pattern of myeloperoxidase (MPO) and plateletperoxidase (PPO) staining is evaluated for the identification of the type of blastic cells during the acute transformation of a chro nic myeloproliferative disorder. MPO and PPO are generally accepted as lineage specific markers for the detection of myeloid or megakaryocyt ic differentiation of the blast cells. The ultrastructural pattern of myeloperoxidase (MPO) and plateletperoxidase (PPO) permitted us to ide ntify two types of blastic cells (one from the myeloid and the other f rom the megakaryoblastic lineage) in the acute transformation of a chr onic myeloproliferative disorders.