W. Plugge et C. Vandervlies, NEAR-INFRARED SPECTROSCOPY AS A TOOL TO IMPROVE QUALITY, Journal of pharmaceutical and biomedical analysis, 14(8-10), 1996, pp. 891-898
Near-infrared spectroscopy, together with a polar qualification system
, is an ideal technique to distinguish between identical pharmaceutica
l substances differing only slightly in chemical or physical character
istics. Among the attractive applications of this powerful combination
are the more precise definition and selection of starting materials u
sed in the manufacturing of medicinal products and its use in blending
validation.