QUANTITATIVE EEG IN TYPE-1 DIABETIC CHILDREN WITH AND WITHOUT EPISODES OF SEVERE HYPOGLYCEMIA - A CONTROLLED, BLIND-STUDY

We investigated the EEG frequency distribution by quantitative EEG (QE EG) in 28 children with type 1 diabetes and 28 age- and sex-matched co ntrol children. Among the diabetic children, 15 had experienced episod es of severe hypoglycemia (SH group) and 13 had not experienced such e pisodes of 14 EEG epochs, each of 4s duration, was performed. QEEG sho wed increased theta activity in the SH group bilaterally in the fronto central region and a slight trend toward more delta activity in diabet ic children than control children bilaterally in the occipital electro des. The relative alpha amplitude was decreased in the SH group at sev eral locations. Abnormal standard EEG (diffuse theta activity) was obs erved in two SH patients and one non-SH patient. All control children had normal standard EEG. We conclude that episodes of severe hypoglyce mia may affect frontocentral function slightly in some diabetic childr en.