Manneristic catatonia, one form of Leonhard's systematic schizophrenia
s, is illustrated in nine case notes. The essential syndrome of this r
are disorder (described by Leonhard in the preneuroleptic era) consist
ed in mannerisms and progressive stiffness of psychomotor activity. Ma
nnerisms often developed from obsessive and compulsive ideas; whereas
distress disappeared, repetitive behaviour developed into a stereotype
, Complex movements (e.g. not to shake hands; mutism) became mannerism
s. With disease progression stiffness of facial expression and gesture
s and an impairment of voluntary motor activity became increasingly pr
ominent. There were no signs of (neuroleptic-induced) parkinsonism. Ma
nneristic catatonia affects preponderantly men and exhibits an early a
ge of onset (median: 23 years). In none of the cases a family history
of psychiatric illness was noted. Severe obstetric and birth complicat
ions as well as the high prevalence of supratentorial and cerebellar C
T/MR abnormalities in this patient group point to deviations of prenat
al brain maturation. The median yearly dose of neuroleptics was 83.1 g
chlorpromazin equivalents. The characteristic psychopathology was not
essentially influenced by modern psychopharmacological treatment neit
her in the beginning nor in the long run irrespective of the time of o
nset of the disease. Continuous high-dose neuroleptic treatment is not
efficacious in this distinct group of systematic schizophrenias. Beha
vioural training in a rehabilitation unit is the treatment of choice f
rom the early beginning.