Efficacy and tolerability of memantine have been evaluated in a post m
arketing surveillance study with 1420 dementia outpatients under the c
onditions of daily medical practice. Already within one month of treat
ment, memantine significantly improved memory, concentration, orientat
ion, mood, sleep and motor functions. In all these functions, further
improvement was achieved in the course of the treatment. Efficacy of m
emantine was rated by the physicians as good/very good in 70%, tolerab
ility in 94% of cases respectively.