M. Michal et al., CARCINOMA ARISING IN ECTOPIC HAMARTOMATOUS THYMOMA - AN ULTRASTRUCTURAL-STUDY, Pathology research and practice, 192(6), 1996, pp. 610-618
We present the ultrastructural features of a case of adenocarcinoma ar
ising in ectopic hamartomatous thymoma in a 31 year old man, in the su
praclavicular location. The tumor had a cribriform adenomatous compone
nt with a granular cell quality and mimicked a metastatic carcinoma. U
ltrastructurally, the spindle cell component revealed clusters of tono
filaments and the tumor cells were attached by well developed desmosom
es. The cytoplasm of adenocarcinoma cells contained peculiar cup-shape
d bodies derived from the endoplasmic reticulum wrapped around the mit
ochondriae.