BACKGROUND: Carcinoma of the stomach continues to cause a significant
mortality in the United States. We reviewed the characteristics, treat
ment modalities, and survival of a group of patients with this cancer
at a tertiary care referral hospital. MATERIALS AND METHODS: A retrosp
ective computer based review of all patients with a diagnosis of carci
noma of the stomach in the Ohio State University (OSU) tumor registry
was made. One hundred ninety-two analytical cases were found and the d
ata was entered into a computerized database and analyzed. RESULTS: Th
e overall median survival in this series of patients is 10 months with
a median survival of 16 months (n.s.) in patients who underwent curat
ive surgery (50% of the patients). There was an increased number of ca
rdia lesion (37%) predominately in male patients (P < 0.05). A signifi
cantly greater number of female patients presented with linitis plasti
ca and male patients with adenocarcinoma, although there was no differ
ence in the operability, types of operations, and survival between the
genders. Patients with signet ring cell cancer were significantly you
nger than the other two histological types reviewed but this did not a
lter outcome. CONCLUSION: Carcinoma of the stomach, despite newer imag
e modalities, continues to present at advanced stages at time of diagn
osis with an overall dismal prognosis. The increased incidence of card
ia lesions noted require innovative therapies if any progress is to be
made.