Sk. Saunders et al., OUTCOMES OF OCULAR EXPOSURES REPORTED TO A REGIONAL POISON CONTROL CENTER, Journal of toxicology. Cutaneous and ocular toxicology, 15(3), 1996, pp. 249-259
Although toxic chemical ocular exposures are common, there has been li
ttle epidemiologic study of this problem. We carried out a systematic
follow-up study of symptomatic ocular exposures reported to a regional
poison control center (PCC). We interviewed 279 (76%) of 368 patients
reported to the PCC that met study criteria. Exposures were heterogen
eous, including personal care and medicinal products, 42 (15%); hydroc
arbon solvents 30 (11%); hypochlorite bleach, 20 (7%); strong acids an
d bases 19 (7%); and all other causes 168 (60%). The median duration t
hat eye irrigation was performed as a first aid measure was 15 min; 20
3 (73%) initiated irrigation within 2 min or less. Only 30 (11%) repor
ted that symptoms persisted longer than 2 days; 85 (31%) were treated
by a physician for the exposure. Taking into account other factors suc
h as type of exposure and extent of involvement, reported increased le
ngth of irrigation time was associated with worse outcome whether meas
ured by number of symptoms (odds ratio [OR] 1.6, 95% confidence interv
al [CI] 1.2-2.2, per 10 min irrigation); symptoms persistent for more
than 2 days (OR 1.8, 95% CI 1.3-2.6); or receipt of physician care (OR
2.3, 95% CI 1.7-3.2). These data show that ocular chemical exposures
reported in PCC case surveillance are heterogeneous and largely self-l
imited. Nonetheless, specific exposure- and treatment-related factors
may predict worse outcome and may warrant further investigation. Epide
miologic assessment of this common cause of ocular morbidity is import
ant to guide prevention activities.