La. Moulopoulos et al., MR PREDICTION OF BENIGN AND MALIGNANT VERTEBRAL COMPRESSION FRACTURES, Journal of magnetic resonance imaging, 6(4), 1996, pp. 667-674
We reviewed spinal MR images of 58 patients with 98 compressed vertebr
ae, Benign (47 vertebrae) or malignant (51 vertebrae) etiology was est
ablished by biopsy or radiologic follow-up, Compressed vertebrae were
analyzed for presence and characteristics of signal abnormality, alter
ed vertebral contour, Schmorl's nodes, pedicular involvement, and cont
rast uptake, Statistical analysis was performed, Diffuse and homogeneo
us decrease in signal intensity on T1-weighted images, convex vertebra
l contour, involvement of the pedicles, and a lumbar location were mor
e frequently observed in malignant fractures (P < .01), A thoracic loc
ation, lack of signal change, or a band-like abnormality and absence o
f pedicular involvement or contour abnormality characterized benign fr
actures (P < .01), Schmorl's nodes and enhancement did not help establ
ish a diagnosis, When a constellation of MR criteria are applied, the
accuracy of the diagnosis of malignant and benign vertebral compressio
n fractures may reach 94%.