ENANTIOMERICALLY PURE 4-METHYL-BICYCLO[3.2.0]HEPT-3-EN-6-OL AND 1,4-DIMETHYL-BICYCLO[3.2.0]HEPT-3-EN-6-OL AND ONES BY MICROBIAL REDOX

Authors
FANTIN G FOGAGNOLO M MAROTTA E MEDICI A PEDRINI P RIGHI P
Citation
G. Fantin et al., ENANTIOMERICALLY PURE 4-METHYL-BICYCLO[3.2.0]HEPT-3-EN-6-OL AND 1,4-DIMETHYL-BICYCLO[3.2.0]HEPT-3-EN-6-OL AND ONES BY MICROBIAL REDOX, Chemistry Letters, (7), 1996, pp. 511-512
Citations number
10
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
7
Year of publication
1996
Pages
511 - 512
Database
ISI
SICI code
0366-7022(1996):7<511:EP4A1>2.0.ZU;2-R
Abstract
The reduction of bicyclo[3.2.0]hept-3-en-6-ones la,b with Baker's yeas t to a mixture of enantiomerically pure (6S)-endo-and (6S)-exo-alcohol s 2a,b and 3a,b respectively is described. Furthermore the oxidation o f the racemic endo-alcohols 2a,b with Bacillus stearothermophilus affo rded the corresponding ketones with high enantiomeric excesses resolvi ng the endo-enantiomer. In the same conditions the exo-alcohols 3a,b a re not oxidized.