Purpose: The cup-to-disc ratio is a widely used clinical measure of op
tic nerve damage in the management of glaucoma patients and those susp
ected of having glaucoma. Knowledge of the optic disc size allows for
a better assessment of the clinical significance of the cup-to-disc ra
tio. In this study, two optical methods -slit-lamp biomicroscopy and c
onfocal scanning laser ophthalmoscopy -were used to measure the vertic
al disc diameter as an indirect measure of optic disc size. The aim wa
s to provide a simple and clinically useful examination technique in t
he management of glaucoma. Methods: The vertical optic disc diameter w
as measured with aspheric lenses (Volk 60, 78, and 90 D, and Nikon 60
and 90 D) using slit-lamp biomicroscopy in 25 emmetropic normal volunt
eers. The average of three readings was determined for each of the len
ses and the measurements were correlated with the magnification-correc
ted diameter measured with the Heidelberg Retina Tomograph. Results: T
he mean vertical disc diameter of the group, as measured with the Heid
elberg Retina Tomograph, was 1.81 +/- 0.18 mm. Results obtained with t
he lower-power lenses correlated best with the Heidelberg Retina Tomog
raph measurements (for example, Volk 60 D: r = 0.80, p = 0.0001, 95% c
onfidence interval 1.76-1.85 mm), whereas the 90-D correlation was the
weakest (for example, Volk 90 D: r = 0.59, p = 0.002, 95% confidence
interval 1.75-1.87 mm). With the Volk 60-D lens, the ''best fit'' equa
tion for estimating disc diameter, in millimetres, is Y = 0.85X + 0.06
, where Y is the Heidelberg Retina Tomograph value and X is the slit-l
amp biomicroscopy measurement. Conclusion: Using these formulae, the c
linician is able to estimate the optic disc diameter with sufficient a
ccuracy to allow clinical decisions to be made in the evaluation of pa
tients with glaucoma, without recourse to expensive technology.