L. Cristofolini et al., A MINIMAL PARAMETRIC MODEL OF THE FEMUR TO DESCRIBE AXIAL ELASTIC STRAIN IN RESPONSE TO LOADS, Medical engineering & physics, 18(6), 1996, pp. 502-514
Evaluating the state of stress/strain for a given geometry and load in
femurs can be done both experimentally, measuring strain at a limited
number of locations, and theoretically with finite element models. An
other approach is to describe the state of strain with a few synthetic
indices. For this purpose the reverse elastic problem (i.e. bone para
meters are estimated given the strain distribution and loads) needs to
be solved as opposed to the finite element direct problem. Such rever
se models can be then used: (1) to describe simply the strain distribu
tion by means of few synthetic indices, (2) to explain the state of st
rain; and (3) to predict the strain distribution under different loadi
ng conditions. Various linear models, characterized by two to five bon
e-related parameters, were tested on (1) 12 femurs, (2) a finite eleme
nt model, and (3) data taken from the literature, for a total of 43 lo
ading cases. Three and four-parameter models were able to fit the expe
rimental strain distributions with mean squared residuals smaller than
5% of the strain range. The consistency of the model was proved by th
e repeatability of the parameters estimate for identical femurs. Furth
ermore the bone-related coefficients were able to detect the stiffenin
g effect of the implantation of an uncemented stem. Finally, the model
can be used for predictive purposes if the parameter estimates are us
ed with different loading conditions. Copyright (C) 1996 Elsevier Scie
nce Ltd for IPEMB.