A NEW CYTOTOXIC COMPOUND FROM A WATER EXTRACT OF CORN

Authors
HAYASHI Y ISHIHARA N TAKAHASHI M FUJII E UENAKAI K MASADA S ICHIMOTO I
Citation
Y. Hayashi et al., A NEW CYTOTOXIC COMPOUND FROM A WATER EXTRACT OF CORN, Bioscience, biotechnology, and biochemistry, 60(7), 1996, pp. 1115-1117
Citations number
11
Categorie Soggetti
Biology,Agriculture,"Biothechnology & Applied Migrobiology","Food Science & Tenology
Journal title
Bioscience, biotechnology, and biochemistry → ACNP
ISSN journal
09168451
Volume
60
Issue
7
Year of publication
1996
Pages
1115 - 1117
Database
ISI
SICI code
0916-8451(1996)60:7<1115:ANCCFA>2.0.ZU;2-K
Abstract
A new cytotoxic compound 2 was isolated from a water extract of corn g erm, Structural elucidation by spectroscopic data and chemical evidenc e fully substantiated 2 to be 11(E)-10-oxo-11-octadecen-13-olide. Comp ound 2 exhibited considerably strong cytotoxic activity against variou s cell lines with IC50 of 0.9-2.8 mu g/ml.