Physiological variation in the population of the environmentally fairl
y homogeneous Middle Dalmatian island (peninsular) area (the islands o
f Brac, Korcula and Hvar and the peninsula of Peljesac) was investigat
ed using data on lung volumes and arterial blood pressure. Relationshi
ps and divergence among the populations were assessed at three levels
involving 34 village populations, 8 regional populations and 4 island
(peninsular) populations. Extensive phenotypic diversity exists at all
three levels, the highest one being at the village level, followed by
the regional and the level of the whole islands, respectively. This d
iversity is interpreted as deriving from different microevolutionary p
ressures at the three levels of population subdivision. The congruence
between physiological variation and migration history, as well as the
significant correlations between physiological, genetic, geographic a
nd linguistic distances say much of the strength of the isolating fact
ors which have affected the genetic structure of the population of thi
s area.