COLONIZATION OF A CALCIUM-PHOSPHATE ELASTIN-SOLUBILIZED PEPTIDE-COLLAGEN COMPOSITE-MATERIAL BY HUMAN OSTEOBLASTS

Authors
ROVIRA A AMEDEE J BAREILLE R RABAUD M
Citation
A. Rovira et al., COLONIZATION OF A CALCIUM-PHOSPHATE ELASTIN-SOLUBILIZED PEPTIDE-COLLAGEN COMPOSITE-MATERIAL BY HUMAN OSTEOBLASTS, Biomaterials, 17(15), 1996, pp. 1535-1540
Citations number
25
Categorie Soggetti
Engineering, Biomedical","Materials Science, Biomaterials
Journal title
Biomaterials → ACNP
ISSN journal
01429612
Volume
17
Issue
15
Year of publication
1996
Pages
1535 - 1540
Database
ISI
SICI code
0142-9612(1996)17:15<1535:COACEP>2.0.ZU;2-N
Abstract
The evaluation of the suitability of a new biomaterial as a possible s ubstitute for bone tissue is described here. This biomaterial is based on calcium phosphate particles linked to an artificial connective mat rix, the elastin-solubilized peptides (ESP) associated with type I and III collagens. This work demonstrates the feasibility of shaping this composite material into discs, describes its microstructural characte ristics, and evaluates its capacity as a substrate for the proliferati on of human osteoblasts without loss of their phenotypic expression. ( C) 1996 Elsevier Science Limited.