METHODOLOGY FOR THE SYNTHESIS OF DINUCLEOSIDE MONOPHOSPHATES CONTAINING A 2'-DEOXY-3-ISOADENOSINE UNIT - 3-ISO-DAGT AND TP(3-ISO-DA)

Authors
LEONARD NJ",NEELIMA
Citation
Leonard Nj",neelima, METHODOLOGY FOR THE SYNTHESIS OF DINUCLEOSIDE MONOPHOSPHATES CONTAINING A 2'-DEOXY-3-ISOADENOSINE UNIT - 3-ISO-DAGT AND TP(3-ISO-DA), Nucleosides & nucleotides, 15(7-8), 1996, pp. 1369-1381
Citations number
33
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
15
Issue
7-8
Year of publication
1996
Pages
1369 - 1381
Database
ISI
SICI code
0732-8311(1996)15:7-8<1369:MFTSOD>2.0.ZU;2-D
Abstract
2'-Deoxy-3-isoadenylyl(3'-5')thymidine and thymidylyl-(3'-5')-2'-deoxy -3-isoadenosine have been synthesized by mild protection/deprotection methodology that circumvents facile N3-Cl' hydrolytic cleavage of the 2'-deoxy-3-isoadenosine moiety.