INDOCYANINE-GREEN ANGIOGRAPHY FEATURES IN POSTERIOR UVEITIS

Background Indocyanine-green (ICG) angiography gives additional inform ation in posterior inflammatory conditions by enabling to analyse the choroid. It may become a useful work-up procedure in inflammatory dise ases predominant ly involving the choroid. Our purpose was to analyse ICG findings and correlate them to fluorescein angiographic and clinic al findings in posterior uveitis. Patients and methods In patients wit h posterior uveitis involving the choroid, ICG angiography is performe d routinely in addition to the usual uveitis work-up. We report on the ICG angiography features found in sarcoidoses (6 cases), birdshot cho rioretinopathy (4 cases), multiple evanescent white dot syndrome (MEWD S, 2 cases), Vogt-Koyanagi-Harada disease (2 cases) and multifocal cho roiditis (2 cases). Results The hypofluorescent lesions characteristic for choroidal lesions were seen in all 5 analyzed entities. They corr esponded either to active inflammatory lesions or to atrophic areas of the choroid. To distinguish between these 2 situations correlation be tween clinical findings, fluorescein angiography and ICG angiography w as necessary. Except for multifocal choroiditis where hypofluorescent areas corresponded essentially to atrophic areas:ICG angiography showe d inflammatory choroidal lesions not seen clinically or by fluorescein angiography. ICG hyperfluorescence in the late phase of angiography s eemed to be a sign for recent or acute inflammatory involvement. Concl usion ICG angiography was helpful to assess choroidal involvement and disease progression in 4 of the posterior inflammatory disorders exami ned and will probably prove useful in the work-up of most posterior uv eitis involving the choroid.