INDUCTION OF MELANOCYTIC NEVI IN 2 CHILDR EN WITH HEMATOLOGICAL MALIGNANCIES AND CHEMOTHERAPY-INDUCED IMMUNOSUPPRESSION

Authors
JAPPE U ABECK D JANKASCHAUB GE GROSS G JAKOB T RING J
Citation
U. Jappe et al., INDUCTION OF MELANOCYTIC NEVI IN 2 CHILDR EN WITH HEMATOLOGICAL MALIGNANCIES AND CHEMOTHERAPY-INDUCED IMMUNOSUPPRESSION, Hautarzt, 47(7), 1996, pp. 537-540
Citations number
27
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
Hautarzt → ACNP
ISSN journal
00178470
Volume
47
Issue
7
Year of publication
1996
Pages
537 - 540
Database
ISI
SICI code
0017-8470(1996)47:7<537:IOMNI2>2.0.ZU;2-K
Abstract
Two children developed multiple melanocytic naevi after polychemothera py administered for acute lymphoblastic leukaemia in one and for non-H odgkin lymphoma in the other. Induction of naevi does not seem to be r elated to specific agents used in chemotherapy, but rather to the immu nosuppression resulting from multiple-agent chemotherapy. There are re ports in the literature of both intrinsically and iatrogenically immun osuppressed patients who have developed multiple melanocytic naevi.