Tuberculous mesenteric lymphadenitis is a rare clinical entity and non
-surgical diagnosis of this condition remains a challenge. A 38-year-o
ld Indian woman presented with a six-week history of epigastric pain,
low-grade fever and anorexia. Upper endoscopy showed a gastric ulcer o
f the posterior wall of the stomach. On CT scan there was a 8 cm abdom
inal mass involving the pancreatic body and tail and the endoscopic ul
trasonography was also compatible with a cystic pancreatic tumor which
had eroded into the stomach. An exploratory laparotomy was performed
and the diagnosis of tuberculous mesenteric lymphadenitis was confirme
d by bacteriological and histological examinations. Medical therapy wa
s started after surgery. At 18 months she is asymptomatic and abdomina
l CT scan is normal. Tuberculosis of mesenteric lymph nodes usually ra
ises serious diagnostic problems. A high grade of suspicion is necessa
ry in order to perform a pre-operative diagnosis.