Background/Aims: This report presents the technique and preliminary re
sults of a prospective trial of videothoracoscopic bilateral truncal v
agotomy without a drainage procedure in a series of selected patients
having elective surgery for chronic non obstructive duodenal ulcer. Ma
terial and Methods: Videothoracoscopic truncal vagotomy was performed
in size patients with chronic duodenal ulcer resistant to medical trea
tment. These patients undergoing neither a drainage nor a dilatation p
rocedure supplementary to bilateral truncal vagotomy were chosen with
selective indication regarding the absence of pyloric obstruction and
presence of hyperacidity. The results of acid secretory tests and endo
scopic control were studied. Results: A Videothoracoscopic approach to
truncal vagotomy was performed simply with a mean operation time of 4
2 min (35-80) providing all the advantages of minimally invasive surge
ry such as low morbidity and early recovery. The mean decrease of peak
acid output was 77.4% and the ulcer healed without any gastric stasis
symptoms or signs as compared with the endoscopic controls at the sec
ond month postoperatively. During the mean. follow-up period of 26 mon
ths (3-38), the only symptom was moderate diarrhea which resolved spon
taneously. Conclusion: Truncal vagotomy by videothoracoscopy as a simp
le, surgeon independent and efficient procedure seems to be an alterna
tive treatment regimen for the management of chronic duodenal ulcer in
a group of selected patients. instead of routine addition. of a drain
age procedure after truncal vagotomy which may improve the morbidity,
observation of the patient after truncal vagotomy with dietary caution
supplementary to prokinetic medication may be the chosen method in to
day's circumstances.