ANALYSIS OF SEROLOGICAL SURVEYS USING MIXTURE-MODELS - APPLICATION TOA SURVEY OF PARVOVIRUS B19

Authors
GAY N
Citation
N. Gay, ANALYSIS OF SEROLOGICAL SURVEYS USING MIXTURE-MODELS - APPLICATION TOA SURVEY OF PARVOVIRUS B19, Statistics in medicine, 15(14), 1996, pp. 1567-1573
Citations number
8
Categorie Soggetti
Statistic & Probability","Medicine, Research & Experimental","Public, Environmental & Occupation Heath","Statistic & Probability","Medical Informatics
Journal title
Statistics in medicine → ACNP
ISSN journal
02776715
Volume
15
Issue
14
Year of publication
1996
Pages
1567 - 1573
Database
ISI
SICI code
0277-6715(1996)15:14<1567:AOSSUM>2.0.ZU;2-4
Abstract
A method for the analysis of age stratified antibody prevalence survey s is developed. The age specific distribution of the quantitative resu lts of serological antibody tests is modelled as a mixture of seroposi tive and seronegative components. This yields maximum likelihood estim ates of the prevalence at each age. The method is illustrated using da ta from a previously reported survey of antibody to parvovirus B19.