Whereas thermal cyclisation of variously substituted 2,3-diarylacrylaz
ides easily provided a new way to 3-aryl-isoquinolones, nitration of t
hese compounds mainly led to corresponding 3-aryl-4-nitro-isoquinolone
s. After reduction into 4-amino-3-aryl-isoquinolones, amidification an
d subsequent cyclization gave the yet unknown title compounds. Copyrig
ht (C) 1996 Elsevier Science Ltd