USE OF PHOSPHAZENE BASE AND PHASE-TRANSFER CONDITIONS FOR REGIOSPECIFIC ALKYLATIVE ISOMERIZATION OF VINYL SULFONES CAPABLE OF UNDERGOING BETA-ELIMINATION REACTIONS
Zd. Jin et Pl. Fuchs, USE OF PHOSPHAZENE BASE AND PHASE-TRANSFER CONDITIONS FOR REGIOSPECIFIC ALKYLATIVE ISOMERIZATION OF VINYL SULFONES CAPABLE OF UNDERGOING BETA-ELIMINATION REACTIONS, Tetrahedron letters, 37(30), 1996, pp. 5249-5252
Using phosphazene base, P-4-t-Bu or basic phase-transfer catalyst cond
itions, vinyl sulfones were regiospecifically alkylated at the alpha-p
osition, No beta-elimination products were observed in a system capabl
e of undergoing anion-promoted beta-elimination. The scope and limitat
ions of these reactions were studied. Copyright (C) 1996 Elsevier Scie
nce Ltd