AN EFFICIENT ACCESS TO (R)-6,6'-DIMETHOXY-2,2'-DIIODO-1,1'-BIPHENYL AND (S)-6,6'-DIMETHOXY-2,2'-DIIODO-1,1'-BIPHENYL

Authors
CEREGHETTI M SCHMID R SCHONHOLZER P RAGEOT A
Citation
M. Cereghetti et al., AN EFFICIENT ACCESS TO (R)-6,6'-DIMETHOXY-2,2'-DIIODO-1,1'-BIPHENYL AND (S)-6,6'-DIMETHOXY-2,2'-DIIODO-1,1'-BIPHENYL, Tetrahedron letters, 37(30), 1996, pp. 5343-5346
Citations number
54
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
30
Year of publication
1996
Pages
5343 - 5346
Database
ISI
SICI code
0040-4039(1996)37:30<5343:AEAT(A>2.0.ZU;2-3
Abstract
In a better procedure than the known for (rac)-2a, the diamine (rac)-2 b was resolved for the first time with the new resolving agent (R,R)- and (S,S)-2,3-di(phenylaminocarbonyl)tartaric acid (5c) (40-45% weight yields; >99% ee). The diamines (R)- or (S)-2a and 2b were converted w ith >98% stereochemical retention into the diiodides (R)- and (S)-3a a nd 3b and subsequently, without loss of optical purify, diphenylphosph inated to the known diphosphines (R)- and (S)-4a and 4b. Copyright (C) 1996 Elsevier Science Ltd