TOTAL SYNTHESIS OF (15S, 16R, 19S, 2OR, 34S)-DIEPOMURICANIN

Authors
KONNO H MAKABE H TANAKA A ORITANI T
Citation
H. Konno et al., TOTAL SYNTHESIS OF (15S, 16R, 19S, 2OR, 34S)-DIEPOMURICANIN, Tetrahedron letters, 37(30), 1996, pp. 5393-5396
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
30
Year of publication
1996
Pages
5393 - 5396
Database
ISI
SICI code
0040-4039(1996)37:30<5393:TSO(11>2.0.ZU;2-S
Abstract
An eleven-step reaction sequence starting from enantiomerically pure ( -)-muricatacin (6) afforded the key intermediate 12, which was then co nverted to (15S, 16R, 19S, 20R, 34S)-diepomuricanin (1) via introducti on of an acetylene unit and a coupling reaction with iodo lactone synt hon 15. Copyright (C) 1996 Elsevier Science Ltd