REPLACEMENT OF THE PHOSPHODIESTER LINKAGE IN OLIGONUCLEOTIDES BY AN ACETYLENIC BOND - COMPARISON BETWEEN CARBON-CONTAINING, SULFUR-CONTAINING, AND OXYGEN-CONTAINING ANALOGS

Authors
WENDEBORN S JOUANNO C WOLF RM DEMESMAEKER A
Citation
S. Wendeborn et al., REPLACEMENT OF THE PHOSPHODIESTER LINKAGE IN OLIGONUCLEOTIDES BY AN ACETYLENIC BOND - COMPARISON BETWEEN CARBON-CONTAINING, SULFUR-CONTAINING, AND OXYGEN-CONTAINING ANALOGS, Tetrahedron letters, 37(31), 1996, pp. 5511-5514
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
31
Year of publication
1996
Pages
5511 - 5514
Database
ISI
SICI code
0040-4039(1996)37:31<5511:ROTPLI>2.0.ZU;2-K
Abstract
Four acetylene-containing dimers were synthesized and incorporated int o oligonucleotides. The hybridization properties of the modified oligo nucleotides to RNA complements and their conformational analysis are r eported. Copyright (C) 1996 Elsevier Science Ltd