STRAIN RELEASE IS NOT ENOUGH

Authors
SELLA A BASCH H HOZ S
Citation
A. Sella et al., STRAIN RELEASE IS NOT ENOUGH, Tetrahedron letters, 37(31), 1996, pp. 5573-5576
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
31
Year of publication
1996
Pages
5573 - 5576
Database
ISI
SICI code
0040-4039(1996)37:31<5573:SRINE>2.0.ZU;2-5
Abstract
The activation barrier for the nucleophilic attack of CW on [1.1.1]-pr opellane is lowered by 60.7 kcal (compared to the strain free analog) while the total strain energy released in the reaction is only 45 kcal showing that strained molecules react faster not only because of part ial strain release at the transition state. Copyright (C) 1996 Elsevie r Science Ltd