TAXOL-INDUCED ACRAL ERYTHEMA

Chemotherapy-induced acral erythema is a peculiar localized cutaneous response to several chemotherapeutic agents, mostly antimetabolites. T axol is a recently developed antineoplastic drug that acts on the mito tic spindle and does not interfere with nucleic acid synthesis. We des cribe the first case of taxol-induced acral erythema and report on add itional data concerning the pathogenesis of this kind of toxic eruptio ns.