Retinal involvement has been documented in a number of patients with p
igment dispersion syndrome, which also appears to be associated with a
higher than normal risk of retinal detachment. We studied 24 patients
with this syndrome to determine the prevalence of lattice degeneratio
n and other retinal disorders associated with a predisposition to deta
chment. Lattice degeneration was found in 8 of 24 patients examined, w
ith a prevalence that is significantly higher than that reported for n
ormal subjects. Four eyes presented areas of retinoschisis and only on
e displayed a rhegmatogenous detachment. A father and son (both myopes
) were found to have similar lattice lesions in the same retinal quadr
ants. These findings suggest that pigment dispersion syndrome may be a
ssociated with developmental anomalies that are not restricted to the
anterior chamber but involve other portions of the bulb as well.