MUCRONINE-J, A 14-MEMBERED CYCLOPEPTIDE ALKALOID FROM ZIZYPHUS-MUCRONATA

Authors
AUVIN C LEZENVEN F BLOND A AUGEVENBOUR I POUSSET JL BODO B CAMARA J
Citation
C. Auvin et al., MUCRONINE-J, A 14-MEMBERED CYCLOPEPTIDE ALKALOID FROM ZIZYPHUS-MUCRONATA, Journal of natural products, 59(7), 1996, pp. 676-678
Citations number
13
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
59
Issue
7
Year of publication
1996
Pages
676 - 678
Database
ISI
SICI code
0163-3864(1996)59:7<676:MA1CAF>2.0.ZU;2-4
Abstract
From the CH2Cl2 extract of the root bark of Z. mucronata (Rhamnaceae), a new cyclopeptide alkaloid, named mucronine J, was isolated together with previously known alkaloids abyssenine A and mucronine D. The str ucture of mucronine J was elucided by mass spectrometry and 1D and 2D NMR. A solution conformation is proposed on the basis of NOE experimen ts in combination with MM2 calculations.