Jm. Jacyno et al., LYCACONITINE REVISITED - PARTIAL SYNTHESIS AND NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTOR AFFINITIES, Journal of natural products, 59(7), 1996, pp. 707-709
The norditerpenoid alkaloid lycaconitine (2) was synthesized from lyco
ctonine (3) and its affinity determined for two neuronal nicotinic ace
tylcholine receptor subtypes. The structure of 2 was confirmed by a co
mbination of spectroscopic methods.