NOVEL FUNCTIONAL POLYMERS - POLY(DIMETHYLSILOXANE)POLYAMIDE MULTIBLOCK COPOLYMER .5. THE INTERACTION BETWEEN BIOMOLECULES AND THE SURFACE OF ARAMID-SILICONE RESINS

Authors
FURUZONO T KISHIDA A YANAGI M MATSUMOTO T KANDA T NAKAMURA T AIKO T MARUYAMA I AKASHI M
Citation
T. Furuzono et al., NOVEL FUNCTIONAL POLYMERS - POLY(DIMETHYLSILOXANE)POLYAMIDE MULTIBLOCK COPOLYMER .5. THE INTERACTION BETWEEN BIOMOLECULES AND THE SURFACE OF ARAMID-SILICONE RESINS, Journal of biomaterials science. Polymer ed., 7(10), 1996, pp. 871-880
Citations number
33
Categorie Soggetti
Engineering, Biomedical","Polymer Sciences","Materials Science, Biomaterials
Journal title
Journal of biomaterials science. Polymer ed. → ACNP
ISSN journal
09205063
Volume
7
Issue
10
Year of publication
1996
Pages
871 - 880
Database
ISI
SICI code
0920-5063(1996)7:10<871:NFP-PM>2.0.ZU;2-4
Abstract
Multiblock copolymers consisting of aromatic polyamide(aramid) and pol y(dimethylsiloxane) (PDMS) aramid-silicone resins (PASs) were synthesi zed by low temperature solution polycondensation, and PAS films were p repared by casting from an N,N'-dimethylacetamide solution. In this st udy, we investigated bovine serum albumin (BSA) adsorption, L929 cell adhesion, and tissue reaction on the surface of PAS in order to clarif y the interaction between PAS and biomolecules. It was found that the amount of adsorbed biomolecules on PAS was extremely low in contrast w ith those on aramid and nylon films, and it was comparable to SILASTIC (R) 500-1 film. This suppression of adsorption of biomolecules onto PA S seemed to be due to the low surface free energy of the outermost sur face of PAS, where PDMS block was condensed.