Gastrointestinal tonometry is supposed to diagnose gut mucosal hypoxia
using gastric luminal PCO2 and arterial bicarbonatemia, which are sub
stituted in a modified Henderson-Hasselbach equation. This article rev
iews some of the problems inherent to the multiple assumptions underly
ing this technique. Tonometry is influenced by several local factors a
nd by systemic acid-base imbalances that are unrelated to oxygenation.
Tonometry is a rather crude and cumbersome method of gut capnometry,
a technology that may provide valuable information regarding visceral
perfusion, but not necessarily oxygenation.