TOTAL SYNTHESIS OF (-7-DEOXYPANCRATISTATIN AND (+)-7-DEOXY-TRANS-DIHYDRONARCICLASINE())

Authors
CHIDA N JITSUOKA M YAMAMOTO Y OHTSUKA M OGAWA S
Citation
N. Chida et al., TOTAL SYNTHESIS OF (-7-DEOXYPANCRATISTATIN AND (+)-7-DEOXY-TRANS-DIHYDRONARCICLASINE()), Heterocycles, 43(7), 1996, pp. 1385-1390
Citations number
33
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
43
Issue
7
Year of publication
1996
Pages
1385 - 1390
Database
ISI
SICI code
0385-5414(1996)43:7<1385:TSO(A(>2.0.ZU;2-5
Abstract
The chiral and stereoselective synthesis of antimitotic phenanthridone alkaloids, (+)-7-deoxypancratistatin (1) and (+)-7-deoxy-trans-dihydr onarciclasine (2) is described. Both natural products were synthesized from the common compound (4), which had been prepared from D-glucose and employed for the synthesis of lycoricidine (3).