Citation
Oa. Attanasi et al., SYNTHESIS OF 3-UNSUBSTITUTED 1-AMINOPYRROLES, Heterocycles, 43(7), 1996, pp. 1447-1457
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
03855414
Volume
43
Issue
7
Year of publication
1996
Pages
1447 - 1457
Database
ISI
SICI code
0385-5414(1996)43:7<1447:SO31>2.0.ZU;2-C
Abstract
3-Unsubstituted 1-aminopyrroles have been obtained by mild reaction of
some alpha-halohydrazones with beta-dicarbonyl compounds in basic med
ium. The reaction takes place by formation of conjugated azoalkene int
ermediate and, in turn, of Michael-type adduct, which cyclizes into ti
tle compounds by subsequent treatment in methanol under reflux, or in
tetrahydrofuran with sulfuric acid at room temperature.