SYNTHESIS OF ACETAMIDO(INDOL-3-YL)PROPANOL DERIVATIVES

Authors
MORALESRIOS MS ZEPEDA LG SUAREZCASTILLO OR JOSEPHNATHAN P
Citation
Ms. Moralesrios et al., SYNTHESIS OF ACETAMIDO(INDOL-3-YL)PROPANOL DERIVATIVES, Heterocycles, 43(7), 1996, pp. 1483-1496
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
43
Issue
7
Year of publication
1996
Pages
1483 - 1496
Database
ISI
SICI code
0385-5414(1996)43:7<1483:SOAD>2.0.ZU;2-Z
Abstract
A series of acetamido(indol-3-yl)propanol derivatives (5-7) has been s ynthesized using a variety of reductive reactions performed on the cor responding O-methyl oximes of an indol-3-yl ester and of several indol -3-yl alcohol derivatives. The O-methyl oximes were prepared in good y ields by acylation of the corresponding zinc salt of indole, followed by O-methyl oximation.